Trypanosoma cruzi mucins: potential functions of a complex structure
نویسندگان
چکیده
منابع مشابه
Trypanosoma cruzi mucins: potential functions of a complex structure.
Departamento de Parasitologia, ICB2, USP, 05508-900 São Paulo, SP, Brasil *Departamento de Bioquímica e Immunologia, UFMG, Belo Horizonte, MG, Brasil **Laboratorio de Doença de Chagas, CPqRR-Fiocruz, Belo Horizonte, MG, Brasil ***Department of Biochemistry, University of Dundee, Dundee, Scotland,United Kingdom ****Departamento de Immunologia, Microbiologia e Parasitologia, Unifesp, São Paulo, S...
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The anti-Trypanosoma cruzi activity of extracts from 13 Argentinean Asteraceae species was determined. Dichloromethane and methanol extracts of Acmella bellidioides, Aspilia silphioides, Viguiera tuberosa, Calyptocarpus biaristatus, Hyalis argentea, Helenium radiatum, Gaillardia megapotamica, Verbesina subcordata, Gymnocoronis spilanthoides, Viguiera anchusaefolia, Thelesperma megapotamicum, Ze...
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Although the genome of Trypanosoma cruzi has been completely sequenced, little is known about its population structure and evolution. Since 1999, two major evolutionary lineages presenting distinct epidemiological characteristics have been recognised: T. cruzi I and T. cruzi II. We describe new and important aspects of the population structure of the parasite, and unequivocally characterise a t...
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Trypanosoma cruzi is wrapped by a dense coat of mucin-type molecules encoded by complex gene families termed TcSMUG and TcMUC, which are expressed in the insect- and mammal-dwelling forms of the parasite, respectively. Here, we dissect the contribution of distinct post-translational modifications on the trafficking of these glycoconjugates. In vivo tracing and characterization of tagged-variant...
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ژورنال
عنوان ژورنال: Memórias do Instituto Oswaldo Cruz
سال: 1999
ISSN: 0074-0276
DOI: 10.1590/s0074-02761999000700023